Position paper
ISGE Statement on Purified and Specific Cytoplasmic Pollen Extract, PureCyTonin® as a non-hormonal alternative for the treatment of menopausal symptoms
Andrea Riccardo Genazzani, Leila Adamyan, Sarah Berga, Martin Birkhaeuser, Mark Brincat, Antonio Cano, Cuauhtemoc Celis, Peter Chedraui, Nilson Roberto De Melo, Blazej Meczekalski, Alfred O. Mueck, Frederick Naftolin, Rossella E. Nappi, Nicola Pluchino, Xiangyan Ruan, Tommaso Simoncini, Nestor Siseles, John Stevenson, Charles Sultan, Basil C. Tarlatzis, Svetlana Vujović, Andrzej Milewicz
Vasomotor symptoms can significantly reduce the quality of life in menopausal women. Current menopausal management guidelines suggest that it is necessary to provide treatment tailored to the individual. Alternative non-hormonal approaches for relief of these symptoms are needed, especially in the presence of contraindications or… Read more ≫
Review
Therapeutic approaches for vasomotor symptoms and sleep disorders in menopausal women
Santiago Palacios, Skouby Sven, Luis Beltrán, Tommaso Simoncini, Cuauhtémoc Celis-Gonzales, Martin Birkhaeuser, Nestor Siseles, Andrea Riccardo Genazzani
Introduction: Vasomotor symptoms and their concomitant sleep disorders affect quality of life and well-being of menopausal women. Menopausal hormone therapy is the first prescribed option for treating vasomotor symptoms such as hot flushes and insomnia. However, menopausal hormone therapy is contraindicated for women with current… Read more ≫
Review
Purified and specific cytoplasm pollen extract for the treatment of vasomotor menopausal symptoms: a review
Nicoletta Biglia, Margherita Giorgi, Roberta Rosso, Marta D’Alonzo, Silvia Actis, Isabella Cipullo, Elisabetta Robba, Valentina Bounous
Background and purpose: In the developed world, vasomotor disorders are the most common menopausal symptoms and hormone replacement therapy (HRT) is the most effective remedy. This review aims to show that the Purified and Specific Cytoplasmic Pollen Extract is an effective and safe alternative in… Read more ≫
Short Review
Tubal factor infertility: which is the possible role of tubal microbiota? A fresh look to a busy corner focusing on the potential role of hysteroscopy
Salvatore Giovanni Vitale, Mislav Mikuš, Mislav Herman, Maurizio Nicola D’Alterio, Marina Šprem Goldštajn, Jan Tesarik, Stefano Angioni
There is a growing body of evidence regarding the importance of the urogenital microbiota associated to reproductive outcomes, both for achieving pregnancy naturally or with the use of assisted reproductive technology (ART). The role of the vaginal and endometrial microbiota in potential infertility can be… Read more ≫
Short Review
Female infertility as a result of stress-related hormonal changes
Andrzej Lewinski, Maria Brzozowska
Introduction: Contemporary civilization provides a number of stress factors, and exposure to these factors disrupts the functioning of many systems of the human body. As a result of stress, organisms activate a complex range of responses involving the endocrine, nervous and immune systems. In normal… Read more ≫
Short Review
Abnormal uterine bleeding in adolescents: causes, challenges and concerns
Saulė Starkauskaitė, Žana Bumbulienė
Abnormal uterine bleeding (AUB) is the most common gynaecologic complaint of adolescents, requiring a good knowledge in terms of etiology and diagnostic methods to provide the best management of the condition. Ovulation disorders, mostly because of hypothalamic-pituitary- ovarian immaturity, is the main cause of AUB…. Read more ≫
Case report
Association of posterior reversible encephalopathy syndrome with gonadotropin-releasing hormone antagonist and iron therapy for anemia and uterine myoma
Shinsuke Hanawa, Michio Sanada, Shiro Sato, Shintaro Obata
We report a case of posterior reversible encephalopathy syndrome in a patient receiving iron preparations for anemia and gonadotropin-releasing hormone antagonists for a uterine myoma. The patient presented with heavy menstrual bleeding (HMB) and anemic hemoglobin levels of 5.4 g/dL who after 40 days was successfully… Read more ≫
Case report
Multiple complications associated with prolonged depot medroxyprogesterone acetate treatment. Case report and mini-review of literature
Wiktoria Witczak, Aleksandra Kukulska, Anna Szeliga, Olga Niwczyk, Blazej Meczekalski, Agnieszka Podfigurna
Depot medroxyprogesterone acetate (DMPA) is an injectable, progestin-only contraceptive that provides highly effective, three-month-long, reversible contraception. It is given every 12 weeks by intramuscular (dose of 150 mg/mL) or subcutaneous (dose of 104 mg/0.65mL) injection. DMPA causes suppression of ovulation by blocking the hypothalamic-pituitary-ovarian (HPO) axis…. Read more ≫
Original articles
Does administration of additional FSH at time of ovulation trigger benefit patients undergoing IVF with PGT-A?
Isaac J. Chamani, David H. McCulloh, Frederick L. Licciardi Frederick L. Licciardi
Background and purpose: Recent reports offer conflicting evidence on the effect of administering additional FSH (boost) on the day of ovulation trigger in IVF cycles. This is a retrospective cohort study evaluating the clinical benefit of a boost on oocyte retrieval, quality, and development, specifically… Read more ≫
Original articles
Retrospective cohort study: urinary estradiol and precocious puberty. Does a correlation exist?
Alice Tassi, Francesca Pampaloni, Pina Mertino, Chiara Meleca, Claudia Tucci, Arianna Bendoni, Patrizia Bordonaro, Sandra Bucciantini, Metella Dei, Vincenzina Bruni, Lorenza Driul, Felice Petraglia
Background and purpose: To evaluate the usefulness of urinary estradiol (E2) assay for the management of patients with precocious puberty. Methods: This was a retrospective cohort study performed in the Obstetrics and Gynaecology Clinic, Careggi Hospital, University of Florence, Florence, Italy. We collected data from… Read more ≫
Original articles
Cost-effectiveness of the three commonly used endometrial preparation methods in women undergoing frozen embryo transfer: a propensity- score matched study
Jayapriya Jayakumaran Jayapriya Jayakumaran, Sejal Dharia Patel, Bhushan K. Gangrade Gangrade, Celso Silva
Background and purpose: To compare the cost-effectiveness of the three commonly used endometrial preparation methods in women undergoing frozen embryo transfer (FET). Methods: This was a retrospective cohort study of FET cycles performed between January 2009 and June 2015 at a tertiary fertility center. Three categories were… Read more ≫